960化工网
Organophosphorus-mediated N–N bond formation: facile access to 3-amino-2H-indazoles†
Hassen Bel Abed,Mathias Christmann
Organic & Biomolecular Chemistry Pub Date : 08/15/2016 00:00:00 , DOI:10.1039/C6OB01544A
Abstract

A convenient and efficient strategy has been devised to access 3-amino-2H-indazole derivatives in two steps from readily available starting materials. The conversion of 2-nitrobenzonitriles to substituted benzamidines followed by an organophosphorus-mediated reductive cyclization and a subsequent N–N bond formation afforded 3-amino-2H-indazoles in good to excellent yields.

Graphical abstract: Organophosphorus-mediated N–N bond formation: facile access to 3-amino-2H-indazoles
平台客服
平台客服
平台在线客服