A simple synthesis of ployfunctionalized mono- and bis-dihydro-2-oxopyrrole derivatives is described by one-pot multi-component reaction of amines, dialkyl acetylenedicarboxylates and formaldehyde in the presence of trityl chloride (10 mol%) at room temperature in EtOH. The features of this procedure are mild and green reaction conditions, good to high yields, short reaction times, high atom economy, operational simplicity and no need for column chromatography.