A new polymer inclusion membrane (PIM) containing cellulose triacetate (CTA) as the monomer, di-tert-butylcyclohexano-18-crown-6 (DtBuCH18C6) as the carrier and 2-nitrophenyl octyl ether (NPOE) as the plasticizer was developed for the selective transport of Sr²⁺ from aqueous nitrate medium. Studies with crown ether concentration variation have indicated a linear dependence on the permeability coefficient (P) suggesting a diffusion mechanism for ion transport. Effects of membrane thickness, nature of plasticizer and plasticizer concentration on the transport of Sr²⁺ were studied. The effect of feed acidity was also investigated for a possible application in the nuclear waste solution. Selective Sr²⁺ transport was observed in a synthetic waste solution containing metal ions such as UO₂²⁺, MoO₂²⁺, Zr⁴⁺, Ce³⁺, Nd³⁺, Ru³⁺, Pd²⁺, Ba²⁺ and Cs⁺, etc., in 1 M HNO₃ and 2 M NaNO₃. Greater than 70% transport of Sr²⁺ was observed in 24 h while most of the other metal ions were negligibly transported (<0.01%).