Manipulation of the stereochemical outcome and product distribution in the Henry reaction using CO2 pressure
Andrew J. Parratt,Dave J. Adams,Anthony A. Clifford,Christopher M. Rayner
Chemical Communications Pub Date : 10/08/2004 00:00:00 , DOI:10.1039/B409451D
Abstract
The rate and stereocontrol of the Henry reaction in the presence of CO2 can be controlled simply by manipulation of CO2 pressure, and can be understood by consideration of the kinetic and thermodynamic aspects of the reaction.