960化工网
Observation by NMR of cationic Wheland-like intermediates in the deiodination of protected 1-iodonaphthalene-2,4-diamines in acidic media†
Elvis A. Twum,Timothy J. Woodman,Michael D. Threadgill
Organic & Biomolecular Chemistry Pub Date : 08/07/2013 00:00:00 , DOI:10.1039/C3OB41386A
Abstract

1-Iodonaphthalene-2,4-diamines in trifluoroacetic acid/chloroform give stable Wheland-like tetrahedral cationic species observable by NMR, through an initial intramolecular protonation. Dynamic equilibria allow proton-deuterium exchange of aromatic protons and provide a mechanism for deiodination of 1-iodonaphthalene-2,4-diamines.

Graphical abstract: Observation by NMR of cationic Wheland-like intermediates in the deiodination of protected 1-iodonaphthalene-2,4-diamines in acidic media
平台客服
平台客服
平台在线客服