NBS-mediated dinitrogen extrusion of diazoacetamides under catalyst-free conditions: practical access to 3-bromooxindole derivatives†
Xiangbo Wang,Kuiyong Dong,Bin Yan,Cheng Zhang,Lihua Qiu
RSC Advances Pub Date : 07/18/2016 00:00:00 , DOI:10.1039/C6RA16868J
Abstract

A synthetically useful transformation arises from NBS-mediated dinitrogen extrusion of N-aryl diazoacetamides under catalyst-free conditions, which gives 3-bromooxindoles in high to excellent yields with high selectivity via a non-carbene process.

Graphical abstract: NBS-mediated dinitrogen extrusion of diazoacetamides under catalyst-free conditions: practical access to 3-bromooxindole derivatives