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One-pot one-step deracemization of amines using ω-transaminases†
Giyoung Shin,Sam Mathew,Minsu Shon,Byung-Gee Kim,Hyungdon Yun
Chemical Communications Pub Date : 06/11/2013 00:00:00 , DOI:10.1039/C3CC43348J
Abstract

In this study, we developed a one-pot one-step deracemization method for the production of various enantiomerically pure amines using two opposite enantioselective ω-TAs. Using this method, various aromatic amines were successfully converted to their (R)-forms (>99%) with good conversion.

Graphical abstract: One-pot one-step deracemization of amines using ω-transaminases
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