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Metal free one-pot synthesis of α-ketoamides from terminal alkenes†
Sayan Dutta,Surya Srinivas Kotha,Govindasamy Sekar
RSC Advances Pub Date : 05/15/2015 00:00:00 , DOI:10.1039/C5RA05671C
Abstract

A practical approach towards the synthesis of α-ketoamides from readily available terminal alkenes (styrenes) has been developed. Use of inexpensive I2/2-iodoxybenzoic acid (IBX) in dimethyl sulphoxide (DMSO) as an oxidant under metal free one-pot conditions makes this methodology versatile.

Graphical abstract: Metal free one-pot synthesis of α-ketoamides from terminal alkenes
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