Manipulating DNA writhe through varying DNA sequences†
Dawei Li,Zhaoqi Yang,Guanjia Zhao,Yi Long,Bei Lv,Cheng Li,Shuhui Hiew,Magdeline Tao Tao Ng,Juanjuan Guo,HongKee Tan,Hao Zhang,Tianhu Li
Abstract
It is demonstrated that the shapes and magnitudes of DNA writhe can be precisely manipulated solely through maneuvering the nucleotide sequence of DNA and without the assistance of topoisomerases.