To determine the transport properties of VS₂ monolayers, we have calculated the current based on the bias voltage, band structure and transmission spectrum for VS₂ monolayers along the zigzag and armchair orientations by first-principles calculations combined with the non-equilibrium Green's function method. A perfect spin filtering effect for the two directions and strong anisotropy have been found. Meanwhile, the zigzag orientation device shows obvious negative differential resistance around a bias voltage of ±0.55 V.