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Microwave-promoted efficient synthesis of C6-cyclo secondary amine substituted purine analogues in neat water†
Gui-Rong Qu,Lin Zhao,Dong-Chao Wang,Jing Wu,Hai-Ming Guo
Green Chemistry Pub Date : 02/04/2008 00:00:00 , DOI:10.1039/B719429C
Abstract

The synthesis of C6-cyclo secondary amine-substituted purine analogues in neat water was achieved with the aid of microwave irradiation, providing a rapid, efficient and convenient method for the preparation of acyclic nucleosides in high yields.

Graphical abstract: Microwave-promoted efficient synthesis of C6-cyclo secondary amine substituted purine analogues in neat water
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