Molecular structure from a single NMR supersequence†
Ēriks Kupče,Tim D. W. Claridge
Chemical Communications Pub Date : 05/25/2018 00:00:00 , DOI:10.1039/C8CC03296C
Abstract

New NOAH supersequences (NMR by Ordered Acquisition using 1H-detection) are introduced that allow fast structure elucidation of organic molecules from a single measurement. The application of the proposed NOAH-3 BSC and NOAH-4 BSCN experiments, combining two new modules (ZZ-HMBC (B) and ASAP-COSY (C)) with multiplicity-edited HSQC (S) and NOESY (N), is exemplified here through their use in computer-assisted structure elucidation.

Graphical abstract: Molecular structure from a single NMR supersequence