Programmable protein–DNA hybrid hydrogels for the immobilization and release of functional proteins†
Yuzhou Wu,Chuang Li,Felix Boldt,Yanran Wang,Seah Ling Kuan,Thuy Tam Tran,Viktoria Mikhalevich,Christina Förtsch,Holger Barth,Zhongqiang Yang,Dongsheng Liu,Tanja Weil
Abstract
A modular approach for the precise assembly of multi-component hydrogels consisting of protein and DNA building blocks is described for the first time. Multi-arm DNA is designed for crosslinking and stepwise, non-covalent assembly of active proteins inside the hydrogel.
