We report the rapid nucleophilic [18F]-radiolabeling of a bodipy dye in aqueous solutions. This radiolabeled dye, whose biodistribution and clearance has been studied in mice, is stable in vivo and can be used as a positron emission tomography/fluorescence dual modality imaging agent.
![Graphical abstract: Rapid aqueous [18F]-labeling of a bodipy dye for positron emission tomography/fluorescence dual modality imaging](http://hg.y866.cn/compound/lib/scimg/usr/1/C1CC13089G.jpg)
