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Monitoring fast reactions by spatially-selective and frequency-shifted continuous NMR spectroscopy: application to rapid-injection protein unfolding†
Gabriel E. Wagner,Peyman Sakhaii,Wolfgang Bermel,Klaus Zangger
Chemical Communications Pub Date : 03/01/2013 00:00:00 , DOI:10.1039/C3CC39107H
Abstract

The repetition rate of an NMR experiment is usually limited by the longitudinal relaxation times of the investigated molecule. Here we show that continuous excitation and data acquisition, without any interscan delay, is possible by a spatially resolved experiment where different nuclei are excited in consecutive scans.

Graphical abstract: Monitoring fast reactions by spatially-selective and frequency-shifted continuous NMR spectroscopy: application to rapid-injection protein unfolding
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