Reactions of organolithiums with dialkyl oxalates. A flow microreactor approach to synthesis of functionalized α-keto esters†
Aiichiro Nagaki,Daisuke Ichinari,Jun-ichi Yoshida
Chemical Communications Pub Date : 03/13/2013 00:00:00 , DOI:10.1039/C3CC40392K
Abstract
Reactions of functionalized aryllithiums with dialkyl oxalates were achieved using a flow microreactor to obtain α-keto esters with high selectivity by virtue of fast 1 : 1 micromixing.
