960化工网
pH-sensitive loaded retinal/indocyanine green micelles as an “all-in-one” theranostic agent for multi-modal imaging in vivo guided cellular senescence-photothermal synergistic therapy†
Lipeng Zhu,Ping Li,Duyang Gao,Jie Liu,Yubin Liu,Chen Sun,Mengze Xu,Xin Chen,Zonghai Sheng,Ruibing Wang,Zhen Yuan,Lintao Cai,Yifan Ma,Qi Zhao
Chemical Communications Pub Date : 05/01/2019 00:00:00 , DOI:10.1039/C9CC02567G
Abstract

In this study, pH-sensitive loaded retinal/indocyanine green (ICG) micelles were developed to realize novel approaches for cellular senescence-photothermal synergistic therapy to treat cancer. The micelles could enable effective multi-modal imaging in vivo guided therapy and show anticancer activity in vitro and in vivo with satisfactory biosafety.

Graphical abstract: pH-sensitive loaded retinal/indocyanine green micelles as an “all-in-one” theranostic agent for multi-modal imaging in vivo guided cellular senescence-photothermal synergistic therapy
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