Covering: mid-1980s up to June 2003

This review covers compounds with activity on African trypanosomes (mainly Trypanosoma brucei subsp., T. congolense and T. vivax) isolated from natural sources and is organized according to the structure of the metabolites (alkaloids, phenolic derivatives, quinones, terpenes and other metabolites). The literature from the mid-1980s up to June 2003 is reviewed and 89 references are cited.