Profiling human Src homology 2 (SH2) domain proteins and ligand discovery using a peptide-hybrid small molecule microarray†
Jiaqi Fu,Zhenkun Na,Shao Q. Yao
Chemical Communications Pub Date : 08/21/2013 00:00:00 , DOI:10.1039/C3CC45413D
Abstract
A 396-member peptide-hybrid small molecule microarray was fabricated to profile small molecule ligands across 15 SH2 proteins, revealing hits against Lck and Grb2.