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ONO pincer type Pd(ii) complexes: synthesis, crystal structure and catalytic activity towards C-2 arylation of quinoline scaffolds†
Vignesh Arumugam,Werner Kaminsky,Dharmaraj Nallasamy
RSC Advances Pub Date : 09/04/2015 00:00:00 , DOI:10.1039/C5RA15342E
Abstract

Four new palladium(II) complexes featuring ONO pincer type hydrazone ligands were synthesized and characterized by spectroscopic and single-crystal XRD analysis. These complexes showed excellent catalytic activity towards the Suzuki–Miyaura cross coupling reaction of 2-chloroquinoline derivatives with various aryl boronic acids. The main advantages over previous methodologies include low catalyst loading, less problematic reaction media (H2O–DMF (80 : 20%)) and a lower reaction temperature of 60 °C for optimal performance.

Graphical abstract: ONO pincer type Pd(ii) complexes: synthesis, crystal structure and catalytic activity towards C-2 arylation of quinoline scaffolds
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