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Rhodamine derived colorimetric and fluorescence mercury(ii) chemodosimeter for human breast cancer cell (MCF7) imaging†
Babli Kumari,Sisir Lohar,Sangita Adhikari,Archya Sengupta,Ansuman Chattopadhyay,Paula Brandão,Vítor Félix,Debasis Das
RSC Advances Pub Date : 02/17/2015 00:00:00 , DOI:10.1039/C4RA14624G
Abstract

Condensation of rhodaminehydrazone with naphthalene-1-carboxaldehyde generates a colourless probe, RDHDNAP that can selectively detect Hg2+ through generation of a pink color along with significant fluorescence enhancement. The binding constant and lowest detection limit for Hg2+ are 2.0 × 105 M−1 and 3 × 10−7 M respectively. Hg2+ imaging in human breast cancer cells (MCF7) under a fluorescence microscope is achieved.

Graphical abstract: Rhodamine derived colorimetric and fluorescence mercury(ii) chemodosimeter for human breast cancer cell (MCF7) imaging
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