n-Bu4NI-catalyzed selective dual amination of sp3 C–H bonds: oxidative domino synthesis of imidazo[1,5-c]quinazolines on a gram-scale†
Dan Zhao,Teng Wang,Qi Shen,Jian-Xin Li
Chemical Communications Pub Date : 03/03/2014 00:00:00 , DOI:10.1039/C4CC01444H
Abstract
An n-Bu4NI catalyzed domino reaction that involves selective dual amination of sp3 C–H bonds has been developed. The protocol affords a facile and efficient approach to the synthesis of imidazo[1,5-c]quinazolines under mild conditions.
![Graphical abstract: n-Bu4NI-catalyzed selective dual amination of sp3 C–H bonds: oxidative domino synthesis of imidazo[1,5-c]quinazolines on a gram-scale](http://hg.y866.cn/compound/lib/scimg/usr/1/C4CC01444H.jpg)
