960化工网
Palladium-catalyzed haloallylation of aromatic ynolethers with allyl chlorides: a highly regio- and stereoselective approach to (1E)-α-chloroenol ethers†
Haiting Cai,Zheliang Yuan,Weidong Zhu
Chemical Communications Pub Date : 06/30/2011 00:00:00 , DOI:10.1039/C1CC13424H
Abstract

Described herein is a Pd-catalyzed haloallylation of aromatic ynol ethers and allyl chlorides, allowing facile access to (1E)-α-chloroenol ethers in a highly regio- and stereoselective manner. The synthetic utility of this method is demonstrated well by the synthesis of the stereodefined multisubstituted enol ethers and α-allylated carbonyl compounds.

Graphical abstract: Palladium-catalyzed haloallylation of aromatic ynol ethers with allyl chlorides: a highly regio- and stereoselective approach to (1E)-α-chloroenol ethers
平台客服
平台客服
平台在线客服