In the last few years, organic dyes have been utilized as an attractive alternative to transition metal catalyzed photocatalysis. Rose Bengal, an organic dye has been widely applied as a photocatalyst in organic synthesis due to its low cost and easy accessibility. In this review, we summarize the key photophysical properties of the dye and its synthetic applications in the formation of C–C and C–X (N, O, S, P, Si, and Se) bonds.