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Pyrrolizidine alkaloids: occurrence, biology, and chemical synthesis
Jeremy Robertson,Kiri Stevens
Natural Product Reports Pub Date : 10/26/2016 00:00:00 , DOI:10.1039/C5NP00076A
Abstract

Covering: 2013 up to the end of 2015

This review covers the isolation and structure of new pyrrolizidines; pyrrolizidine biosynthesis; biological activity, including the occurrence of pyrrolizidines as toxic components or contaminants in foods and beverages; and formal and total syntheses of naturally-occurring pyrrolizidine alkaloids and closely related non-natural analogues.

Graphical abstract: Pyrrolizidine alkaloids: occurrence, biology, and chemical synthesis
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