One-pot three component synthesis of heteroarylated arylacetates viaVNSAr-SN reaction using N-methylpyrrolidone as general solvent†
Song Cao,Jingjing Wu,Lina Li,Longjie Zhu,Jian Zhang,Jinlong Yu,Xuhong Qian
Organic & Biomolecular Chemistry Pub Date : 02/27/2008 00:00:00 , DOI:10.1039/B719185E
Abstract

An efficient three component one-pot method was developed to assemble 2-heteroaryl-2-aryl acetates viaVNSAr-SNAr and VNSAr-SN reaction by using N-methylpyrrolidone (NMP) as general solvent.

Graphical abstract: One-pot three component synthesis of heteroarylated arylacetates viaVNSAr-SN reaction using N-methylpyrrolidone as general solvent