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Revealing the nature of thio-click reactions on the solid phase†
M. Talha Gokmen,Jérémy Brassinne,R. Arun Prasath,Filip E. Du Prez
Chemical Communications Pub Date : 03/21/2011 00:00:00 , DOI:10.1039/C0CC05340F
Abstract

Thiol- and yne-functionalized beads were manufactured in a simple microfluidic setup. While CuAAC and thiol–yne reactions were performed on yne-functionalized beads, 9 different thiol–X reactions were compared, in terms of kinetics and conversion, on thiol-functionalized beads.

Graphical abstract: Revealing the nature of thio-click reactions on the solid phase
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