Rapid assembly of highly-functionalised difluorinated cyclooctenones viaring-closing metathesis
Benson M. Kariuki,W. Martin Owton,Jonathan M. Percy,Stéphane Pintat,Clive A. Smith,Neil S. Spencer,Andrew C. Thomas,Martin Watson
Abstract
Building block methodology from trifluoroethanol and ring-closing metathesis using a Fürstner modification of Grubbs′ conditions allows the rapid synthesis of novel difluorinated cyclooctenones.
