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One-pot vinylogous aldol addition of β,γ-unsaturated esters under mild conditions†
İsmail Akçok,Ali Çağır
New Journal of Chemistry Pub Date : 05/22/2015 00:00:00 , DOI:10.1039/C5NJ00961H
Abstract

We described a one-pot vinylogous aldol addition of methyl 3-butenoate to aromatic aldehydes in the presence of silver salts and the TMSCl–TBAF mixture. The reaction can be done simply by sequentially mixing reagents in situ, and it does not require any catalyst or dienolate ether preparations prior to the reaction.

Graphical abstract: One-pot vinylogous aldol addition of β,γ-unsaturated esters under mild conditions
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