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Platinum-catalysed cinnamaldehyde hydrogenation in continuous flow†
Lee J. Durndell,Karen Wilson,Adam F. Lee
RSC Advances Pub Date : 09/09/2015 00:00:00 , DOI:10.1039/C5RA14984C
Abstract

Platinum is one of the most widely used hydrogenation catalysts. Here we describe the translation of batch reactions to continuous flow, affording tunable C[double bond, length as m-dash]O versus C[double bond, length as m-dash]C hydrogenation over a Pt/SiO2 catalyst, resulting in high steady state activity and single-pass yields in the selective hydrogenation of cinnamaldehyde to cinnamyl alcohol under mild conditions. Negligible catalyst deactivation occurs under extended flow operation due to removal of reactively-formed poisons from the reaction zone. Process intensification imparts a four-fold enhancement in cinnamyl alcohol productivity.

Graphical abstract: Platinum-catalysed cinnamaldehyde hydrogenation in continuous flow
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