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Palladium(ii)-catalysed tandem cyclisation of electron-deficient aromatic enynes†
Antonios Messinis,Andrei S. Batsanov,Zhen Yang,Andrew Whiting
Chemical Communications Pub Date : 08/22/2012 00:00:00 , DOI:10.1039/C2CC35114E
Abstract

A novel palladium(II) catalysed tandem cyclisation of substituted 2-alkenylphenyl alkynones gives substituted 2-vinyl indenones and 6,5,6-fused tricyclic lactone skeletons (pyrones), in one-pot. Wagner–Meerwein-like rearrangements were observed which occur preferentially to conventional chloride-mediated chloropalladations of enynes.

Graphical abstract: Palladium(ii)-catalysed tandem cyclisation of electron-deficient aromatic enynes
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