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Palladium-catalyzed direct C–H arylation of ferrocenecarboxamides with aryl halides†
Huijie Qiao,Suyan Sun,Fan Yang,Yu Zhu,Weiguo Zhu,Yangjie Wu
RSC Advances Pub Date : 06/13/2016 00:00:00 , DOI:10.1039/C6RA11972G
Abstract

A simple and facile protocol for the palladium-catalyzed ortho-arylation of ferrocenecarboxamides with aryl halides was developed with the assistance of the bidentate directing group. The substrate scope could be extended to aryl iodides, bromides and even chlorides, as well as heterocyclic halides, affording diarylated products in moderate to good yields.

Graphical abstract: Palladium-catalyzed direct C–H arylation of ferrocenecarboxamides with aryl halides
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