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Spontaneous mirror symmetry breaking in heterocatalytically coupled enantioselective replicators†
Albert Moyano,David Hochberg
Chemical Science Pub Date : 09/13/2016 00:00:00 , DOI:10.1039/C6SC02446G
Abstract

Chiral hypercycle replicators (first-order autocatalysis together with mutual cross-catalysis) formed from achiral or racemizing resources may lead to spontaneous mirror symmetry breaking (SMSB) without the need for additional heterochiral inhibition reactions, such as those of the Frank-like models, which are an obstacle for the emergence of evolutionary selection properties. The results indicate that the chemical models for the emergence of primordial autocatalytic self-reproducing systems, of and by themselves, can also explain naturally the emergence of biological homochirality.

Graphical abstract: Spontaneous mirror symmetry breaking in heterocatalytically coupled enantioselective replicators
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