Palladium(ii)-catalyzed intermolecular oxidative C-3 alkenylations of imidazo[1,2-a]pyridines by substrate-contolled regioselective C–H functionalization†,10.1039/C4RA09669J

热搜：

Lactoyl-CoA 全氟丁基戊烷白叶藤碱全氟己基辛烷新白叶藤碱壳寡糖特色专题-生物多肽

Palladium(ii)-catalyzed intermolecular oxidative C-3 alkenylations of imidazo[1,2-a]pyridines by substrate-contolled regioselective C–H functionalization†

Hua Cao,Sai Lei,Jinqiang Liao,Jianping Huang,Huifang Qiu,Qinlin Chen,Shuxian Qiu,Yaoyi Chen

RSC Advances Pub Date : 09/30/2014 00:00:00 , DOI:10.1039/C4RA09669J

Abstract

An efficient and highly regioselective palladium(II)-catalyzed oxidative C-3 alkenylation of imidazo[1,2-a]pyridines with acrylate, acrylonitrile, or vinylarenes has been developed by using oxygen as an oxidant. Substrates such as acrylate and acrylonitrile tended to form β-product, while vinylarenes tended to form the sole α-products.