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Palladium-catalyzed cyanide metathesis: utilization of benzyl cyanide as an operator-benign reagent for aryl halide cyanations†
Qiaodong Wen,Jisong Jin,Binbin Hu,Ping Lu,Yanguang Wang
RSC Advances Pub Date : 06/25/2012 00:00:00 , DOI:10.1039/C2RA20770B
Abstract

Benzyl cyanide was disclosed to be a safe and effective cyanation reagent for palladium-catalyzed cyanation of haloarenes, which afforded aryl nitriles in moderate to good yields.

Graphical abstract: Palladium-catalyzed cyanide metathesis: utilization of benzyl cyanide as an operator-benign reagent for aryl halide cyanations
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