Palladium-catalyzed intermolecular oxidative cyclization of N-aryl enamines with isocyanides through double sp2 C–H bonds cleavage: facile synthesis of 4-aminoquinoline derivatives†
Qiang Zheng,Puying Luo,Yuqing Lin,Wenfan Chen,Xiuxiu Liu,Yadong Zhang,Qiuping Ding
Abstract
An efficient method for the synthesis of 4-aminoquinolines via palladium-catalyzed intermolecular oxidative cyclization of N-aryl enamines and isocyanides through double sp2 C–H bonds cleavage has been developed.
