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Piperazic acid-containing natural products: Isolation, biological relevance and total synthesis
David J. France,Tatjana Hofmann,Georg Wuitschik,Steven V. Ley
Natural Product Reports Pub Date : 07/05/2011 00:00:00 , DOI:10.1039/C1NP00041A
Abstract

Covering: up to 2010

Since their first discovery in 1959, natural products containing the piperazic acid motif have been isolated from a variety of sources and exhibit diverse biological activity profiles. This review provides information about their isolation and biological activities, and presents an overview of recent total syntheses of these molecules.

Graphical abstract: Piperazic acid-containing natural products: Isolation, biological relevance and total synthesis
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