Specific interactions between silver(i) ions and cytosine–cytosine pairs in DNA duplexes†
Akira Ono,Shiqi Cao,Humika Togashi,Mitsuru Tashiro,Takashi Fujimoto,Tomoya Machinami,Shuji Oda,Yoko Miyake,Itaru Okamoto,Yoshiyuki Tanaka
Abstract
Very specific binding of the Ag(I) ion unexpectedly stabilized DNA duplexes containing the naturally occurring cytosine–cytosine (C–C) mismatch-base pair; because the C–C pair selectively binds to the Ag(I) ion, we developed a DNA-based Ag(I) sensor that employed an oligodeoxyribonucleotide containing C–C pairs used for Ag(I) binding sites.
