Structure and stability of hexadentate complexes of ligands based on AAZTA for efficient PET labelling with gallium-68†
Bradley P. Waldron,David Parker,Carsten Burchardt,Dmitry S. Yufit,Melanie Zimny,Frank Roesch
Chemical Communications Pub Date : 11/14/2012 00:00:00 , DOI:10.1039/C2CC37544C
Abstract
Pre-organised tricarboxylate ligands based on 6-amino-perhydro-1,4-diazepine bind 68Ga rapidly and selectively in acetate buffer at pH 4 to 7, forming kinetically stable complexes suitable for use in PET imaging.
