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Synthesis of 3-aryl-1H-indazoles via iridium-catalysed C–H borylation and Suzuki–Miyaura coupling†
Ben A. Egan,Paul M. Burton
RSC Advances Pub Date : 06/11/2014 00:00:00 , DOI:10.1039/C4RA04235B
Abstract

The regioselective iridium-catalysed C3-borylation of 1H-indazoles has been achieved. Subsequent Suzuki–Miyaura coupling of the boronate esters with aryl chlorides, bromides and iodides affords 3-aryl-1H-indazoles in good yields.

Graphical abstract: Synthesis of 3-aryl-1H-indazoles via iridium-catalysed C–H borylation and Suzuki–Miyaura coupling
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