Suitability of porous silicon microparticles for the long-term delivery of redox-active therapeutics†
Elizabeth C. Wu,Jennifer S. Andrew,Alex Buyanin,Joseph M. Kinsella
Chemical Communications Pub Date : 04/18/2011 00:00:00 , DOI:10.1039/C1CC10993F
Abstract
Thermal oxidation of porous Si microparticles provides an inert carrier for the long-term release of the anthracyclinedrugdaunorubicin. Without prior oxidation, porous Si undergoes an undesirable side reaction with this redox active drug.