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Synthesis of novel lidocaine-releasing poly(diol-co-citrate) elastomers by using deep eutectic solvents†
M. Concepción Serrano,María C. Gutiérrez,Ricardo Jiménez,M. Luisa Ferrer,Francisco del Monte
Chemical Communications Pub Date : 11/22/2011 00:00:00 , DOI:10.1039/C1CC15284J
Abstract

Poly(octanediol-co-citrate) elastomers containing high loading of lidocaine were synthesized at temperatures below 100 °C by means of using deep eutectic mixtures of 1,8-octanediol and lidocaine. The preservation of lidocaine integrity resulted in high-capacity drug-eluting elastomers.

Graphical abstract: Synthesis of novel lidocaine-releasing poly(diol-co-citrate) elastomers by using deep eutectic solvents
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