960化工网
Reactions of 1-alkyl-1,2-diphospholes with 1,3-dipoles: diphenyldiazomethane and nitrones†
Almaz Zagidullin,Yulia Ganushevich,Vasili Miluykov,Dmitry Krivolapov,Oleg Sinyashin,Evamarie Hey-Hawkins
Organic & Biomolecular Chemistry Pub Date : 05/15/2012 00:00:00 , DOI:10.1039/C2OB25532D
Abstract

The reaction of 1-alkyl-1,2-diphosphacyclopenta-2,4-dienes (1-alkyl-1,2-diphospholes) (1) with diphenyldiazomethane proceeds at room temperature via unstable [3+2] cycloadducts to form bicyclic phosphiranes (2). However, 1-alkyl-1,2-diphospholes (1) react with N,alpha-diphenylnitrone or N-tert-butyl-alpha-phenylnitrone depending on the temperature to give either dimers of 1-alkyl-1-oxo-1,2-diphospholes (5) or 1-alkyl-1,7-dioxo-6-azo-1,7-diphospha-bicyclo[3.2.0]hept-2-enes (7) – phosphorus analogues of β-lactams.

Graphical abstract: Reactions of 1-alkyl-1,2-diphospholes with 1,3-dipoles: diphenyldiazomethane and nitrones
平台客服
平台客服
平台在线客服