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A thiol–thiosulfonate reaction providing a novel strategy for turn-on thiol sensing†
Chunpo Ge,Hao Wang,Baoxin Zhang,Juan Yao,Xinming Li,Weimin Feng,Panpan Zhou,Yawen Wang,Jianguo Fang
Chemical Communications Pub Date : 08/18/2015 00:00:00 , DOI:10.1039/C5CC05390K
Abstract

The first thiol-specific turn-on probe, BODIPY-TS, utilizing a thiosulfonate scaffold as the thiol recognition unit was reported. BODIPY-TS displays low toxicity, and features high sensitivity, fast response and quantitative reaction towards thiols. The structural novelty of BODIPY-TS would guide the development of novel thiol probes.

Graphical abstract: A thiol–thiosulfonate reaction providing a novel strategy for turn-on thiol sensing
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