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Regioselective Pd-catalyzed hydroamination of substituted dienes
Arnaud Perrier,Michel Ferreira,Joost N. H. Reek,Jarl Ivar van der Vlugt
Catalysis Science & Technology Pub Date : 02/19/2013 00:00:00 , DOI:10.1039/C3CY00024A
Abstract

The regioselective addition of hydrazones and related N-nucleophiles to substituted terpene-based substrates can be steered to either 1,2- or 1,4-addition products, making this a potentially powerful protocol for the preparation of amines from biorelevant feedstocks via C–N bond formation.

Graphical abstract: Regioselective Pd-catalyzed hydroamination of substituted dienes
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