Targeted delivery of a novel peptide–docetaxel conjugate to MCF-7 cells through neuropilin-1 receptor: reduced toxicity and enhanced efficacy of docetaxel†,10.1039/C5RA16741H

热搜：

Lactoyl-CoA 全氟丁基戊烷白叶藤碱全氟己基辛烷新白叶藤碱壳寡糖特色专题-生物多肽

Targeted delivery of a novel peptide–docetaxel conjugate to MCF-7 cells through neuropilin-1 receptor: reduced toxicity and enhanced efficacy of docetaxel†

Abhijit Saha,Saswat Mohapatra,Prashant Kurkute,Batakrishna Jana,Jayita Sarkar,Prasenjit Mondal

RSC Advances Pub Date : 10/22/2015 00:00:00 , DOI:10.1039/C5RA16741H

Abstract

We have designed a novel peptide–docetaxel conjugate, which delivers docetaxel specifically to cancer cell targeting neuropilin-1 (NRP-1) receptor, thus enhancing its efficacy and acts more aggressively in breast cancer cells.