3′,4′-trans-Linked bicyclic nucleosides locked in S-type conformations
Helena Thomasen,Michael Meldgaard,Morten Freitag,Michael Petersen,Jesper Wengel,Poul Nielsen
Chemical Communications Pub Date : 08/12/2002 00:00:00 , DOI:10.1039/B205031E
Abstract
A novel class of 3′,4′-trans-linked bicyclic nucleosides with locked S-type furanose conformations is introduced by synthesis of two model derivatives; one was obtained by cyclic ether formation and the other by ring-closing metathesis methodology.
