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Synthesis of benzofurans via ruthenium-catalyzed redox-neutral C–H functionalization and reaction with alkynes under mild conditions†
Zhi Zhou,Guixia Liu,Yangyang Shen,Xiyan Lu
Organic Chemistry Frontiers Pub Date : 09/16/2014 00:00:00 , DOI:10.1039/C4QO00196F
Abstract

Using an oxidizing directing group, a mild RuII-catalyzed direct coupling of N-phenoxypivalamide with internal alkynes was developed, generating the benzofurans in moderate to high yields.

Graphical abstract: Synthesis of benzofurans via ruthenium-catalyzed redox-neutral C–H functionalization and reaction with alkynes under mild conditions
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