Synthesis of crystalline (±)-A58365B—an inhibitor of angiotensin-converting enzyme
Chemical Communications Pub Date : 01/01/1900 00:00:00 , DOI:10.1039/CC9960001463
Abstract
A58365B 1, an inhibitor of angiotensin-converting enzyme, is synthesized from two subunits, spiro lactone 5 and ε-hydroxynorleucine methyl ester 6, by a process based on enyne radical cyclization (9a,b → 11a,b).
