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Synthesis of indoles and tryptophan derivatives via photoinduced nitrene C–H insertion†
Lukas Junk,Uli Kazmaier
Organic & Biomolecular Chemistry Pub Date : 02/12/2016 00:00:00 , DOI:10.1039/C5OB02563J
Abstract

Functionalized indoles and tryptophans can be obtained from stannylated alkenes and o-iodoanilines via Stille coupling. Subsequent azidation and photochemical nitrene generation results in the formation of the heterocyclic ring systems via C–H insertion.

Graphical abstract: Synthesis of indoles and tryptophan derivatives via photoinduced nitrene C–H insertion
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